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Sports

NFL Week 10 picks: Rams get revenge on 49ers; Eagles defeat Packers

Details
06 November 2025
Sam Farmer NFL picks
 (Tim Hubbard / Los Angeles Times)

Los Angeles Times NFL writer Sam Farmer examines the matchups and makes his predictions for Week 10 of the NFL season.

All lines and over/under numbers are according to FanDuel Sportsbook.

Last week, Farmer posted a 10-4 (.714) record. Through the first nine weeks of the season, he is 88-47 (.652).

Using point spreads with the scores Farmer predicted, his record against the spread in Week 9 would have been 6-8 (.423). For the season, his record against the spread is 67-68 (.496).

All times are Pacific and TV reflects broadcasts in the Los Angeles area. The Bengals, Chiefs, Cowboys and Titans are off.

Raiders (2-6) at Broncos (7-2)

Denver Broncos quarterback Bo Nix passes against the Houston Texans on Nov. 2.
Denver Broncos quarterback Bo Nix passes against the Houston Texans on Nov. 2. (Eric Gay / Associated Press)

Tonight, 5:15. TV: Amazon Prime.

Line: Broncos by 9½. O/U: 42½.

The Broncos’ defense is elite up front, leading the league in sacks by a wide margin. Bo Nix has become a steady closer, and Denver’s offense is showing balance. Expect the Raiders to hang around before fading late.

Pick: Broncos 27, Raiders 17

Falcons (3-5) vs. Colts (7-2)

Sunday, 6:30 a.m. TV: NFL Network.

Line: Colts by 6½. O/U: 48½.

The Falcons’ offense continues to sputter with turnovers and missed chances, while the Colts’ ground game and physicality give them an edge in Berlin. Indianapolis figures to bounce back after a sloppy loss.

Pick: Colts 28, Falcons 23

Giants (2-7) at Bears (5-3)

Sunday, 10 a.m. TV: Fox.

Line: Bears by 3½. O/U: 47½.

The Giants play hard defensively but lack firepower, whereas the Bears’ young offense keeps improving. Chicago’s pass rush will make the difference at home, especially with the Giants lacking weapons.

Pick: Bears 24, Giants 20

Bills (6-2) at Dolphins (2-7)

Buffalo Bills quarterback Josh Allen passes against the Kansas City Chiefs on Nov. 2.
Buffalo Bills quarterback Josh Allen passes against the Kansas City Chiefs on Nov. 2. (Jeffrey T. Barnes / Associated Press)

Sunday, 10 a.m. TV: NFL Ticket.

Line: Bills by 9½. O/U: 49½.

The Bills found new life coming off their bye, while Miami continues to struggle in big games. Expect Buffalo to control both lines of scrimmage, and Josh Allen will find ways to punch holes in that defense.

Pick: Bills 34, Dolphins 21

Ravens (3-5) at Vikings (4-4)

Sunday, 10 a.m. TV: NFL Ticket.

Line: Ravens by 4½. O/U: 47½.

The Vikings are starting to click behind rookie quarterback JJ McCarthy. Huge win over Detroit on Sunday. But Lamar Jackson and the Ravens’ balance on offense prove too much in a tight one.

Pick: Ravens 28, Vikings 24

Browns (2-6) at Jets (1-7)

Sunday, 10 a.m. TV: NFL Ticket.

Line: Browns by 2½. O/U: 37½.

Both defenses dominate, and points will be hard to come by. Cleveland’s defensive front and run game tilt the field just enough against a Jets team coming off its only win.

Pick: Browns 14, Jets 10

Patriots (7-2) at Buccaneers (6-2)

Sunday, 10 a.m. TV: CBS.

Line: Buccaneers by 2½. O/U: 48½.

The Patriots are finding ways to win but still make too many mistakes. Second-year quarterback Drake Maye is terrific. Tampa Bay, rested and healthier after a bye, edges New England behind a balanced attack.

Pick: Buccaneers 28, Patriots 24

Saints (1-8) at Panthers (5-4)

Carolina Panthers quarterback Bryce Young passes against the Green Bay Packers on Nov. 2.
Carolina Panthers quarterback Bryce Young passes against the Green Bay Packers on Nov. 2. (Mike Roemer / Associated Press)

Sunday, 10 a.m. TV: NFL Ticket.

Line: Panthers by 5½. O/U: 39½.

The Panthers have quietly found consistency with or without Bryce Young at quarterback and an opportunistic defense. The Saints, once in the “buy now” phase, are currently in the “pay later” phase.

Pick: Panthers 27, Saints 21

Jaguars (5-3) at Texans (3-5)

Sunday, 10 a.m. TV: NFL Ticket.

Line: Texans by 1½. O/U: 38½.

Quarterback Davis Mills can’t keep pace with a confident Jaguars defense that’s playing at a high level. Jacksonville is coming off a one-point win over the shaky Raiders, but should pick up this road victory.

Pick: Jaguars 23, Texans 17

Cardinals (3-5) at Seahawks (6-2)

Sunday, 1:05 p.m. TV: NFL Ticket.

Line: Seahawks by 6½. O/U: 45½.

The Seahawks are emerging as a dark-horse contender to go deep in the playoffs, playing tough defense and moving the ball efficiently. The Cardinals’ quarterback carousel continues to sink the team.

Pick: Seahawks 34, Cardinals 20

Rams (6-2) at 49ers (6-3)

Rams quarterback Matthew Stafford passes during a win over the New Orleans Saints at SoFi Stadium on Nov. 2.
Rams quarterback Matthew Stafford passes during a win over the New Orleans Saints at SoFi Stadium on Nov. 2. (Allen J. Schaben / Los Angeles Times)

Sunday, 1:25 p.m. TV: Fox.

Line: Rams by 3½. O/U: 50½.

Matthew Stafford stays hot and leads a statement win over the Niners. Even with Christian McCaffrey rolling, the Rams’ defense rises late. Still, out-coaching Kyle Shanahan would be a feat.

Pick: Rams 27, 49ers 23

Lions (5-3) at Commanders (3-6)

Sunday, 1:25 p.m. TV: NFL Ticket.

Line: Lions by 8½. O/U: 49½.

The Commanders’ offense figures to crumble after losing their starting quarterback, and Marcus Mariota can’t consistently sustain drives. Detroit bounces back strong from a loss, and rolls.

Pick: Lions 34, Commanders 20

Steelers (5-3) at Chargers (6-3)

Chargers quarterback Justin Herbert scrambles during a win over the Minnesota Vikings at SoFi Stadium on Oct. 23.
Chargers quarterback Justin Herbert scrambles during a win over the Minnesota Vikings at SoFi Stadium on Oct. 23. (Eric Thayer / Los Angeles Times)

Sunday, 5:20 p.m. TV: NBC, Peacock.

Line: Chargers by 3. O/U: 45½.

The Steelers’ turnover luck runs out against a healthier Chargers team. Even without Joe Alt, and the offensive line constantly in flux, Justin Herbert does enough to protect home turf.

Pick: Chargers 27, Steelers 24

Eagles (6-2) at Packers (5-2-1)

Monday, 5:15 p.m. TV: ABC, ESPN.

Line: Packers by 2½. O/U: 44½.

The Eagles have won two in a row, and seem to be on fairly stable ground. The Packers respond to last Sunday’s letdown versus Carolina with renewed focus. Go with the more seasoned quarterback.

Pick: Eagles 24, Packers 21

Get the best, most interesting and strangest stories of the day from the L.A. sports scene and beyond from our newsletter The Sports Report.

This story originally appeared in Los Angeles Times.

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Jacoby Brissett lowers his interception rate to an NFL all-time record 1.3 percent

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06 November 2025

Since taking over for the injured Kyler Murray, Cardinals quarterback Jacoby Brissett has thrown just one interception in his 112 pass attempts this season. And in the process he has lowered his already low career interception percentage to a rate unprecedented in NFL history.

Through Monday night's win over the Cowboys, Brissett has thrown 25 career interceptions in 1,873 pass attempts. That's an interception rate of 1.3 percent, the NFL's all-time record.

The second-lowest interception rate in NFL history belongs to Aaron Rodgers, who has thrown an interception on 1.4 percent of his passes.

Brissett's ability to avoid interceptions is one of the reasons Cardinals head coach Jonathan Gannon has talked about how pleased he is with the way the offense has performed with Brissett — while tiptoeing around actually saying he thinks Brissett is playing better than Murray. The Cardinals have put Murray on injured reserve and are continuing to avoid explicitly saying who will start once Murray's injured foot is fully healed. But if there's any chance of Murray getting the starting job back, it's safe to say that has more to do with Murray's status as a first overall pick in the draft who has a contract guaranteeing him $39.8 million next year than with the Cardinals' coaches actually thinking their offense runs better with Murray than with Brissett.

Brissett has not been a great quarterback during his 10-year NFL career, and has more often been a backup than a starter. But he's been the kind of backup who can be relied upon not to throw the game away. And that's a trait that sometimes earns a starting job for a quarterback who had been a backup.

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Dowdle fined for 'two-pump' pelvic thrust celebration

Details
06 November 2025
Rico Dowdle celebrates scoring a touchdown for the Carolina Panthers against the Green Bay Packers in November 2025
Rico Dowdle (right) is in his sixth season in the NFL and currently has 14 career touchdowns [Reuters]

Carolina Panthers running back Rico Dowdle has been fined for an "excessive celebration" featuring two pelvic thrusts.

After scoring a touchdown during Sunday's win at the Green Bay Packers, Dowdle was penalised for unsportsmanlike conduct.

That resulted in a 15-yard penalty, pushing back the extra-point attempt, and although the kick was missed, the Panthers clinched a 16-13 win with a field goal as time expired.

According to ESPN, 27-year-old Dowdle has also been fined $14,491 (£11,095).

The call against Dowdle disproved a supposed NFL rule demonstrated in a Key & Peele comedy sketch in 2013.

The NFL's list of prohibited acts includes taunting, any violent gesture such as simulating a gun and "prolonged or excessive celebrations or demonstrations by an individual player or multiple players''.

In the Key & Peele sketch an American football referee, played by Jordan Peele, would throw the penalty flag for a 'three-pump' celebration by Keegan-Michael Key's character Hingle McCringleberry, but two pumps was deemed acceptable.

Key responded on social media, saying: "Rico! Man, you got robbed - you only did two pumps. I'm sorry, man. Now we're gonna have to write a new sketch."

Carolina coach Dave Canales said on Sunday: "We've got to make sure that we understand the rules. I might have to call up Keegan-Michael Key to get clarification on that part of it.

"But from what I understand, any kind of movement that way, any weapons, or all that stuff is going to get flagged. We've got to be smarter about that."

  • What we learned from the first half of the NFL season
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Read more …

More Articles …

  1. What we learned from the first half of the NFL season
  2. Saints sign RB Audric Estime from the practice squad to the active roster
  3. Chargers place Joe Alt on IR, open Da'Shawn Hand's practice window
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