Fantasy Football Injury Report Week 10: Brian Thomas Jr. ruled out, updates on Puka Nacua, Tory Horton
Staying up to date on NFL injury news is of the utmost importance for fantasy football success. The article below tracks all fantasy-relevant players currently listed on their team's injury report, and provides fantasy managers with actionable recommendations as new information rolls in.
Check back for updates from Tuesday through Saturday.
Don’t forget: Check out the Rotoworld player news feed for all the latest news, notes, and transactions around the league.
**UPDATED AS OF SATURDAY, NOVEMBER 8TH AT 4 PM ET**
AFC East
◆ Buffalo Bills
James Cook - RB (ankle/foot)
Cook picked up a foot/ankle injury in the Bills' Week 9 game against the Chiefs. He was removed from the injury report Friday and will play against the Dolphins.
Fantasy Impact: The Dolphins allow the fifth-most yards per carry (5.0) among NFL defenses in addition to one of the highest explosive run rates in the league, setting Cook up well for another RB1 week.
Joshua Palmer - WR (knee/ankle)
Palmer injured his ankle and knee early in the second quarter of the team's Week 6 loss to the Falcons. He did not return to the game and was labeled as "week-to-week" by head coach Sean McDermott. He did not play in Week 8 or 9, but returned to practice on Wednesday in Week 10. He is listed as questionable for the team's game against the Dolphins.
Fantasy Impact: Palmer has failed to meaningfully upgrade the Bills' receiving corps when healthy. He does not need to be in starting lineups.
◆ Miami Dolphins
Tyreek Hill - WR (knee)
Hill suffered a dislocated knee in the team's Week 4 win over the Jets. His season is over.
Fantasy Impact: Hill's absence likely places additional emphasis on the short-to-intermediate areas of the field, increasing the expected target volume for De'Von Achane, Darren Waller, and Jaylen Waddle. Malik Washington is likely to step into a secondary role and could see his aDOT improve, making him a sneaky potential FLEX option for the remainder of the season. Waddle returned a 6-110-1 line on nine targets in his first game without Hill in Week 5, making him a weekly WR2 option for the remainder of the season.
Darren Waller - TE (pectoral)
Waller managed just 28% of the team's offensive snaps before departing with a pectoral injury in Week 7. He was placed on injured reserve on Wednesday.
Fantasy Impact: Waller's absence leaves additional snaps available for Tanner Conner, although he is unlikely to warrant fantasy consideration in a difficult matchup.
Ollie Gordon - RB (ankle)
Gordon picked up an ankle injury in the team's Week 9 loss to the Ravens on Thursday Night Football. He was limited at practice the following Wednesday and is listed as questionable for Week 10.
Fantasy Impact: Gordon was labeled "day-to-day" by head coach Mike McDaniel on Friday, meaning it is possible he doesn't miss any game time with the injury as the team comes off a mini-bye after playing on Thursday. An absence could force the team to utilize Jaylen Wright in the change of pace role behind starter De'Von Achane when the Dolphins host the Bills in Week 10.
Jaylen Waddle - WR (foot)
Waddle is practicing in full this week, despite suffering a new injury. He was removed from the injury report Friday and will play against the bills.
Fantasy Impact: Waddle can be expected to play through injury once again, against the Bills.
◆ New England Patriots
Rhamondre Stevenson - RB (knee)
Stevenson appeared on Wednesday's injury report as a non-participant and missed the team's Week 9 win over the Falcons. He remains sidelined as of Week 10's Wednesday practice and was ruled out Friday.
Fantasy Impact: Rookie running back TreVeyon Henderson started in Stevenson's stead, though fellow backup running back Terrell Jennings scored the team's lone rushing score against the Falcons.
Kayshon Boutte - WR (hamstring)
Boutte revealed, via his personal Discord server, that he suffered a Grade 1 hamstring strain in Week 9. He was subsequently labeled as "day-to-day" by head coach Mike Vrabel, but remained sidelined on Wednesday. Boutte was ruled out Friday.
Fantasy Impact: Per Vrabel, rookie wide receiver Kyle Williams will "get a greater opportunity here, moving forward." Williams can be stashed in deep leagues at this time, with Boutte evidently heading toward an absence this weekend.
◆ New York Jets
Garrett Wilson - WR (knee)
Wilson hyperextended his knee in the team's Week 6 loss to the Broncos, before missing Weeks 7-8. The Jets were on bye in Week 9. He practiced in a limited capacity to begin the week, in Week 10. He is listed as questionable despite logging a full practice Friday.
Fantasy Impact: Wilson's absence appears to be nearing an end as head coach Aaron Glenn stated Monday that the veteran alpha would practice this week. Fantasy managers patiently await the return of their WR1.
Braelon Allen - RB (knee)
Allen suffered a "pretty serious" knee injury on a kickoff return in the second quarter of the team's Week 4 loss to the Dolphins. He is out indefinitely.
Fantasy Impact: Allen has been a significant contributor in the red zone this season. His absence substantially boosts Breece Hall's upside, who is now a locked-in RB1 in Week 5 against the Cowboys. Backup running back Isaiah Davis can be stashed in 12-team leagues as a high-upside contingency option. Hall gained a season-high 155 yards from scrimmage on 18 opportunities in his first game without Allen in Week 5.
Josh Reynolds - WR (hip)
Reynolds was evidently placed on injured reserve in Week 10, after suffering a hip injury during practice in Week 8.
Fantasy Impact: Reynolds' absence clears the way for new Jets wide receiver Adonai Mitchell to be active on game day.
AFC North
◆ Baltimore Ravens
The Ravens find themselves healthy as they make a push for the playoffs in the second half of the season.
◆ Cincinnati Bengals
Joe Burrow - QB (toe)
Burrow suffered a Grade III turf toe injury in Week 1. He underwent successful surgery and is likely to miss the next three months.
Fantasy Impact: The Bengals signed veteran Joe Flacco on Tuesday. He started in Week 6 and immediately stabilized the offense as a whole.
Mike Gesicki - TE (pectoral)
Gesicki was placed on injured reserve after suffering a pectoral injury in Week 6. He will miss at least four games.
Fantasy Impact: Fellow tight end Tanner Hudson also departed the team's Week 6 loss with a concussion and Drew Sample is dealing with a knee injury. Hudson was limited at Week 8's Wednesday practice. Noah Fant is TE1-viable for as long as he remains the Bengals' lone, healthy tight end.
Samaje Perine - RB (ankle)
Perine was labeled "week-to-week" with a high-ankle sprain.
Fantasy Impact: The Cincinnati backfield has been less than stellar from a fantasy perspective in 2025, although starter Chase Brown saw a ridiculous 96% snap rate after Perine departed in Week 9. Rookie Tahj Brooks is on hand to soak up change of pace duties for as long as Perine remains sidelined.
◆ Cleveland Browns
Cedric Tillman - WR (hamstring)
The Browns' No. 2 wide receiver strained his hamstring in Week 4. He was placed on injured reserve shortly thereafter and returned to practice as a full participant in Week 10. He was activated from injured reserve Saturday and is in line to return to the field against the Jets.
Fantasy Impact: Tillman is stuck in a low-volume passing offense and does not need to be rostered in 12-team leagues, though he can speculatively stashed, for those wishing to role the dice. Browns rookie wide receiver Isaiah Bond (foot) is sidelined as of Wednesday.
◆ Pittsburgh Steelers
The Steelers remain relatively healthy ahead of a Week 10 showdown with the Chargers on Sunday Night Football.
AFC South
◆ Houston Texans
Joe Mixon - RB (foot)
Mixon was placed on the Non-Football Injury list ahead of Week 1 and is eligible to be activated in Week 5. The team stated that the veteran back is "making progress" and will be re-evaluated in a few weeks.
Fantasy Impact: Veteran Nick Chubb is now in a game script-dependent rushing role, while rookie Woody Marks plays on passing downs and in trailing game scripts. The team kept Marks on the field, in scoring position, late in their Week 7 loss to the Seahawks, notably involving Marks on three straight plays that culminated in a receiving touchdown.
Cade Stover - TE (foot)
The Texans placed Stove on injured reserve before Week 2.
Fantasy Impact: Stover will miss at least four games. His absence should add one or two targets to tight end Dalton Schultz's weekly workload. The uptick is not enough to make Schultz a reliable TE1.
C.J. Stroud - QB (concussion)
Stroud left the team's Week 9 loss to the Broncos with a concussion and was placed in the league's protocol. He was ruled out for Week 10 on Wednesday.
Fantasy Impact: Backup Davis Mills completed 17-of-30 passes for 137 yards in relief, peppering the short areas of the field to wide receiver Nico Collins and tight end Dalton Schultz. The fantasy value of the primary skill position players take a hit with Mills at the helm.
Nick Chubb - RB (foot)
The Texans added Chubb to the injury report with a foot injury on Wednesday. Chubb suffered a season-ending broken foot in Week 15 last year. Whether he injured the same foot is currently unknown. He was removed from the injury report Friday after logging a full practice and will play against the Jaguars.
Fantasy Impact: No. 2 running back Woody Marks must be rostered everywhere. He would be an RB2 with RB1 upside if he were allowed to operate as the team's featured running back.
Dalton Schultz - TE (knee/shoulder)
Schultz was limited on Wednesday but was removed from the injury report Friday.
Fantasy Impact: Schultz continues to play through injury. He is a high-end TE2 against the Jaguars this weekend.
◆ Indianapolis Colts
Anthony Richardson - QB (eye)
Richardson suffered a "freak accident" ahead of Week 6 in which an elastic band snapped a piece of metal hit him in the eye, fracturing his orbital bone. He was placed on injured reserve.
Fantasy Impact: Richardson has been off the fantasy radar all season with Daniel Jones' career reemergence. Backup quarterback Riley Leonard can be stashed in superflex leagues, if need be.
Michael Pittman Jr. - WR (glute)
Pittman was added to the injury report on Wednesday. He did not practice. He notably practiced in full while dealing with a glute injury in Week 2, but suited up on game day against the Broncos. He was removed from the injury report Friday following consecutive full sessions to end the week.
Fantasy Impact: Pittman remains a viable WR3 ahead of a matchup with the Falcons.
◆ Jacksonville Jaguars
Brenton Strange - TE (hip)
Strange was unable to finish the team's Week 5 game against the Chiefs due to a hip injury. The team placed him on injured reserve the very next day. He will be eligible to return in Week 11.
Fantasy Impact: Strange currently stands as fantasy's TE20 in PPR scoring, but his 15.3% team target share ties for second among Jaguars pass catchers. Journeyman Hunter Long stepped into the primary pass-catching role following Strange's departure, but he is unlikely to become a viable starter. Fantasy managers should expect the Jaguars' established wide receivers and running backs to compete for chunks of Strange's vacated target share.
Brian Thomas Jr. - WR (ankle)
Thomas suffered a high-ankle sprain in Week 9. He did not practice the following Wednesday and was ruled out for Week 10 on Friday.
Fantasy Impact: Thomas has already dealt with wrist and shoulder injuries in an extremely disappointing season this year.
Dyami Brown - WR (concussion)
Brown was removed from the team's Week 9 win over the Raiders to be evaluated for a concussion. He was limited at Week 10's first practice and removed from the injury report Friday.
Fantasy Impact:Parker Washington saw a team-high nine targets in the overtime win over the Raiders in Week 9. As noted above, Thomas also suffered a high-ankle sprain. The team notably acquired wide receiver Jakobi Meyers via trade this week. The muddied situation is difficult to read, with none of the bunch profiling as even a reliable WR3.
◆ Tennessee Titans
Calvin Ridley - WR (hamstring)
Ridley strained his hamstring in Week 6 and has been unable to suit up on game day since then. He did not play in Week 9.
Fantasy Impact: Rookie wide receivers Elic Ayomanor and Chimere Dike and rookie tight end Gunnar Helm benefited the most in Ridley's absence, although a Week 10 bye could afford the veteran alpha enough time to return to the field when the team hosts the Texans in Week 11.
AFC West
◆ Denver Broncos
Marvin Mims - WR (concussion)
Mims has been ruled out for Week 10, marking his second game missed following the concussion he suffered in Week 8.
Fantasy Impact: It could be difficult for Mims to clear concussion protocol before the team's Thursday Night Football meeting with the Raiders. Troy Franklin saw the biggest boost in snap rate and route participation against the Texans, drawing a team-high 10 targets in the win.
◆ Kansas City Chiefs
Isiah Pacheco - RB (knee)
Pacheco is considered "week-to-week" after spraining his MCL in Week 8 against the Commanders.
Fantasy Impact: Chiefs running back Kareem Hunt operated as the early-down rusher and goal-line back in Pacheco's absence, finding paint for the fifth time this season against the Bills. The team's Week 10 bye could afford Pacheco enough time to return when they take the field against the Broncos in Week 11, but fantasy managers can continue to ride Hunt should Pacheco's absence extend through the bye.
◆ Las Vegas Raiders
The Raiders find themselves healthy as they prepare to face the Broncos on Thursday Night Football in Week 10.
◆ Los Angeles Chargers
Najee Harris - RB (Achilles)
Harris ruptured the Achilles tendon in his left leg during the Chargers' Week 3 win over the Broncos. His season is done.
Omarion Hampton - RB (ankle)
Hampton was placed on injured reserve this week after suffering an ankle injury in the team's Week 5 loss to the Commanders. He will miss the next four games, at minimum. Recent reports indicate he was still in a walking boot following the team's Week 8 win over the Vikings and will not have his practice window opened until after the team's Week 12 bye.
Fantasy Impact: Running back Kimani Vidal continues to operate as the team's clear lead back after handling a 64% snap rate or higher in all four games following Hampton's injury. That said, season-ending injuries to both tackles has influenced the team's ability to consistently run the football, resulting in sporadic fantasy production from Vidal.
NFC East
◆ Dallas Cowboys
Miles Sanders - RB (ankle/knee)
Sanders was injured in Week 4 and did not play in Week 5. He was ruled out for Week 6 before being placed on injured reserve, ending his season.
Fantasy Impact: Veteran Javonte Williams continues to operate in a near workhorse role. Jaydon Blue should still be stashed on benches after faring well in pass-protection in limited action.
◆ New York Giants
Malik Nabers - WR (knee)
Nabers suffered a torn ACL in the team's Week 4 win over the Chargers and will miss the remainder of the 2025 season.
Fantasy Impact: The injury could not have come at a worse time for the Giants after they moved to rookie quarterback Jaxson Dart under center. Nabers' absence will make it difficult to consistently move the football, lowering the upside of all remaining healthy players. Nabers makes for a solid trade target for dynasty managers looking to rebuild this season.
Cam Skattebo - RB (ankle)
Skattebo suffered a gruesome dislocated ankle in the team's Week 8 loss to the Eagles, ending his season.
Fantasy Impact: The backfield in New York should revert to a timeshare headed by veteran Tyrone Tracy in Skattebo's absence. Devin Singletary remains on hand for change-of-pace duties. Treat Tracy as a low-end RB2 for the remainder of the season.
Theo Johnson - TE (shoulder)
Johnson was limited on Wednesday but was removed from the injury report Friday.
Fantasy Impact: Johnson is on track to play this week and remains a weekly, low-end TE1.
◆ Philadelphia Eagles
The Eagles are healthy coming out of their bye ahead of a Week 10 matchup against the Packers.
◆ Washington Commanders
Noah Brown - WR (groin, knee)
Brown was placed on injured reserve in Week 7.
Fantasy Impact: Wide receivers Jaylin Lane, Luke McCaffrey and Chris Moore are splitting the vacated role, making them difficult to trust as re-draft FLEX options. McCaffrey's 2.84 yards per route run notably lead the team by 1.05. His exceptional per-play efficiency could earn him more work as the season progresses.
Jayden Daniels - QB (elbow)
Daniels dislocated the elbow in his left, non-throwing arm in the team's Week 9 loss to the Seahawks. The team said there is no timetable for his return, but the second-year quarterback could have avoided a season-ending injury after X-rays revealed he avoided a fracture. He was ruled out for Week 10.
Fantasy Impact:Marcus Mariota will start for the Commanders for the foreseeable future, slightly denting the fantasy upside of all primary skill position players in the process. Fantasy managers in a bind could do worse than taking a flier on Mariota, considering his rushing upside.
Terry McLaurin - WR (quad)
McLaurin aggravated his quad injury in Week 8. He did not play in Week 9 against the Seahawks and is not expected to play in Week 10 against the Lions. He was ruled out on Friday.
Fantasy Impact: Commanders wide receiver Deebo Samuel, tight end Zach Ertz and, to some degree, running back Jeremy McNichols have proven themselves as the most reliable remaining pass catchers.
Jacory Croskey-Merritt - RB (tooth)
Croskey-Merritt had dental work done this week. He was removed from the injury report Friday and will play in Week 10.
Fantasy Impact: It is not expected to impact the run-centric rookie running back's Week 10 availability.
NFC North
◆ Chicago Bears
Cole Kmet - TE (concussion)
Kmet exited Week 9 against the Bengals. He was limited on Wednesday. He was removed from the injury report Friday and will play against the Giants.
Fantasy Impact: Rookie tight end Colston Loveland erupted for a 6-118-2 receiving line against the Bengals, including the game-winning, 58-yard touchdown late in the fourth quarter. Lovelend appears to be the tight end to own in fantasy out of Chicago moving forward.
Luther Burden - WR (concussion)
Burden is practicing in full for Week 10 against the Giants.
Fantasy Impact: Burden appears likely to return to his modest role against the Giants.
D’Andre Swift - RB (groin)
Swift missed the team's Week 9 win over the Bengals with a groin issue he has been managing for over three weeks. He practiced in a limited capacity on Wednesday but missed Friday's practice with a personal matter before being listed as questionable.
Fantasy Impact: It was rookie Kyle Monangai who stepped into a featured role in the backfield in Week 9 with Roschon Johnson also out. Monangai vaults into RB2 status for as long as Swift remains sidelined. A timeshare is possible, upon Swift's return.
DJ Moore - WR (groin/hip)
Moore sat out on Wednesday, per usual.
Fantasy Impact: None, barring a setback.
Rome Odunze - WR (heel/ankle)
Odunze has been playing ineffectually through the heel issue for weeks. The ankle issue is new. He did not practice on Wednesday but was removed from the injury report Friday.
Fantasy Impact: Odunze can only be treated as a highly volatile weekly starter until he gets back on track, in good health. It would be unsurprising to see the Bears shut him down for a week to get right.
◆ Detroit Lions
The Lions remain relatively healthy through nine weeks.
◆ Green Bay Packers
Jayden Reed - WR (collarbone/foot)
Reed fractured his collarbone in the Packers' Week 2 game against the Commanders and was already playing through a Jones fracture in his foot. When news of the expected collarbone surgery broke, the Packers were reportedly hoping to get Reed back in November. Reed then revealed that he underwent surgery to correct his Jones fracture as well. It is unknown whether this will extend his recovery timeline.
Fantasy Impact: Reed can be stashed in injured reserve spots, but he does not need to be held in leagues without them.
Matthew Golden - WR (shoulder)
Golden was labeled as "day-to-day" by head coach Matt LaFleur on Monday and is listed as questionable for Monday Night Football against the Eagles.
Fantasy Impact: Golden has yet to take on a featured role in the Green Bay offense, a role that only lessened with the return of Christian Watson in Week 8. Fantasy managers can send the rookie to the bench in the immediate future. Dontayvion Wicks and Savion Williams are also listed as questionable. Christian Watson and Malik Heath could each see additional run.
Tucker Kraft - TE (knee)
Kraft suffered a season-ending torn ACL in the team's Week 9 loss to the Panthers.
Fantasy Impact: Kraft's breakout season comes to an end prematurely after the untimely knee injury. Luke Musgrave should be rostered in all formats as he likely enters a featured role for the Packers.
◆ Minnesota Vikings
Aaron Jones - QB (shoulder/toe)
Jones reportedly suffered an AC joint sprain in the team's Week 9 win over the Lions. Evidently, he picked up a toe injury as well. He did not practice on Wednesday and is listed questionable after limited sessions to end the week.
Fantasy Impact: Jones indicated he intends to play in Week 10, although fantasy managers will want to track his practice status this week ahead of a meeting with the Ravens. An absence would once again thrust Jordan Mason into a featured role.
Carson Wentz - QB (shoulder)
Wentz will undergo season-ending surgery after playing through a dislocated shoulder and torn labrum.
Fantasy Impact: Second-year quarterback J.J. McCarthy is the starter in Minnesota moving forward.
Don’t forget: Check out the Rotoworld player news feed for all the latest news, notes, and transactions around the league.
NFC South
◆ Atlanta Falcons
The Falcons returned to full health for their Week 9 loss to the Patriots.
◆ Carolina Panthers
Rico Dowdle - RB (quad)
Dowdle was sidelined on Wednesday after injuring his quad in Week 9. He was removed from the injury report Friday and will play in Week 10.
Fantasy Impact: Dowdle was visibly in pain during the game. Panthers head coach Dave Canales indicates Dowdle will return to practice on Thursday, which would put him on track to play in Week 10. No. 2 running back Chuba Hubbard must be rostered.
Tetairoa McMillan - WR (hamstring)
McMillan is listed as questionable for Week 10 after being added to the injury report Friday with a hamstring injury.
Fantasy Impact: Fantasy managers will want to track his status closely ahead of inactives considering the late-week addition. This is now the third hamstring issue McMillan has dealt with during his rookie season. An absence would likely vault Jalen Coker into fantasy utility.
◆ New Orleans Saints
Kendre Miller - RB (ACL)
Miller suffered a torn ACL in the team's Week 7 loss to the Bears. His season is over.
Fantasy Impact: Rookie Devin Neal should step into the primary change-of-pace role for the Saints in Miller's absence. Lead back Alvin Kamara saw the highest snap rate since Week 2 following Miller's departure and could be again looking at a workhorse role moving forward.
Alvin Kamara - RB (ankle)
Kamara was limited on Wednesday and drew a questionable tag after staying in that status throughout the week.
Fantasy Impact: The once-capable veteran running back will likely be active on game day, though he can only be viewed as a shaky RB3.
◆ Tampa Bay Buccaneers
Chris Godwin Jr. - WR (fibula)
Godwin was sidelined in Weeks 6-8. The team was on bye in Week 9, yet Godwin remains limited as of Wednesday. He was ruled out Friday.
Fantasy Impact: See below.
Mike Evans - WR (collarbone, concussion)
Evans suffered a broken collarbone in the team's Week 7 loss to the Lions. He is expected to miss "most of the season."
Fantasy Impact: Evans managed to play just under two quarters before the injury after returning from three missed contests due to a hamstring injury. Considering the current state of the roster, rookie Emeka Egbuka is looking like a true league-winner.
Bucky Irving - RB (foot/shoulder)
Irving is considered week-to-week after injuring his foot in Week 4. He has not yet returned to practice. He was ruled out Friday.
Fantasy Impact: Fill-in starting running back Rachaad White out-touched fellow back running back Sean Tucker just 15-12 prior to the team's Week 9 bye. Both players are currently on the FLEX radar.
Jalen McMillan - WR (neck)
McMillan remains on injured reserve with a neck injury suffered in the preseason.
Fantasy Impact: The Buccaneers are reeling at wide receiver with McMillan, Chris Godwin and Mike Evans out.
NFC West
◆ Arizona Cardinals
Kyler Murray - QB (foot)
Murray injured his foot on a fourth-quarter fumble in Week 5. He was placed on injured reserve in Week 10 and will be eligible to return in Week 14 against the Rams, though it could be as the Cardinals' backup.
Fantasy Impact: Quarterback Jacoby Brissett has finished as a QB1 in his last three games. He remains a viable streamer.
Trey Benson - RB (knee)
Benson has already undergone surgery after injuring his meniscus in Week 4. He is expected to miss 4-to-6 weeks, but is not expected to return in Week 10.
Fantasy Impact: It was Emari Demercado with the hot hand in Week 9, although Bam Knight remained involved. This appears to be a messy situation for fantasy purposes in the immediate future.
James Conner - RB (ankle)
Conner suffered a season-ending foot injury in Week 3.
Fantasy Impact: See: Trey Benson.
◆ Los Angeles Rams
Puka Nacua - WR (chest)
Nacua suffered a chest injury that is labeled a fractured rib in the team's Week 9 win over the Saints. Rams head coach Sean McVay said Nacua should be good to go in Week 10 against the 49ers after undergoing "scans" on Tuesday. He was removed from the injury report Friday and will play against the 49ers.
Fantasy Impact: Nacua continues to pick up various injuries but currently expect him to be on the field come Sunday. He is an elite WR1.
Tutu Atwell - WR (hamstring)
The Rams placed Atwell on injured reserve Monday.
Fantasy Impact:Jordan Whittington is in line to soak up WR3 duties, if active, for a Rams offense heavily concentrated amongst Nacua, Davante Adams, and running back Kyren Williams. Whittington is listed as questionable with a back injury for Week 10.
◆ San Francisco 49ers
Brock Purdy - QB (toe)
Purdy is considered week-to-week after suffering a setback in Week 4. He is listed as questionable for Week 10 after remaining limited throughout the week.
Fantasy Impact: 49ers backup quarterback Mac Jones remains a high-end QB2 while Purdy is sidelined. The 49ers will likely keep Purdy sidelined until he is consistently practicing in full, so as to avoid another re-injury.
Ricky Pearsall - WR (knee)
Pearsall has not yet returned to practice since suffering a PCL sprain in Week 4. He was ruled out for Week 10 on Friday.
Fantasy Impact: Wide receiver Jauan Jennings is the position group's lone consistently fantasy-relevant player.
◆ Seattle Seahawks
Cooper Kupp - WR (heel/hamstring)
Kupp sat out in Week 9 after picking up a hamstring injury at Thursday's practice. He remains sidelined on Wednesday and is listed as questionable for Week 10.
Fantasy Impact: Kupp traveled with the team last week, seemingly indicating that the hamstring injury is not considered serious. His continued absence from practice could indicate otherwise. Kupp's role is jeopardized by recent trade acquisition, wide receiver Rashid Shaheed.
AJ Barner - TE (calf)
Barner was limited on Wednesday and is listed as questionable for Week 10.
Fantasy Impact: Early-week participation is a good sign, but this one is worth following closely. Rookie tight end Elijah Arroyo would vault onto the TE1 radar if Barner cannot play.
Tory Horton - WR (groin, shin)
Horton was added to the injury report Thursday with multiple ailments and is listed doubtful for Week 10.
Fantasy Impact: It's unfortunate timing for the blazing rookie after his breakout performance in Week 9. Both Jake Bobo and Dareke Young have been ruled out, leaving the team with recent addition Rashid Shaheed potentially alone on the depth chart behind alpha Jaxon Smith-Njigba. Expect the team to elevate multiple wide receivers for game day in Week 10.