Vikings-Browns has the lowest over-under of the 2025 NFL season
The Vikings and Browns will meet on Sunday in London. Carson Wentz vs. Dillon Gabriel. Don't expect much offense.
The over-under for the Vikings-Browns game is set at 36.5, which is the lowest total for any game so far this season.
Previously, the lowest total for the 2025 season was 38 for the Week One game between the Steelers and Jets. In that one, the over hit easily as the Steelers won 34-32.
With Joe Flacco at quarterback, the Browns have averaged 14 points a game, which ranks 31st in the NFL. Gabriel could give their offense a spark, but the more likely result is that Gabriel can't put many points on the board, while the Browns' defense keeps them in a close and low-scoring game.
Thursday Night Football: How to watch the San Francisco 49ers vs. L.A. Rams NFL game tonight
NFC West rivals the San Francisco 49ers and the L.A. Rams are in a heated battle for first place in their division, with both teams, along with the Seattle Seahawks, currently heading into Week 5 with a 3-1 record. The 49ers will head to SoFi Stadium for a Thursday Night Football game against the Rams where the current tie for first will be broken. Rams QB Matthew Stafford, who suffered a back injury that threatened his participation earlier this season, hasn't let it stop him from passing his 385th career touchdown this past weekend. 49ers quarterback Brock Purdy, who dealt with an injured toe in recent weeks, is not confirmed to play in Thursday's game; if he's on the injured list, Mac Jones will start.
The 49ers vs. Rams game will stream live nationally on Amazon Prime Video tonight at 8:15 p.m. ET. Keep reading to find out what you need to know about Thursday's game, and the rest of the Week 5 schedule.
How to watch the San Francisco 49ers vs. Los Angeles Rams game
Date: Thursday, Oct. 2, 2025
Coverage start time: 7 p.m. ET
Kickoff time: 8:15 p.m. ET/5:15 p.m. PT
Game: San Francisco 49ers vs. L.A. Rams
Location: SoFi Stadium, Los Angeles
Streaming:Prime Video
What channel is the 49ers vs. Rams game on?
The 49ers visit the Rams tonight, Oct. 2, for the next Thursday Night Football game of the season, streaming on Amazon's Prime Video.
How to watch Thursday Night Football: San Francisco 49ers vs. L.A. Rams
Rams vs. 49ers: How to watch, prediction and betting odds
Rams wide receiver Davante Adams celebrates after scoring a touchdown against the Indianapolis Colts on Sept. 28. (Robert Gauthier / Los Angeles Times)
The Rams shut down Saquon Barkley. They neutralized Jonathan Taylor.
Now here comes Christian McCaffrey.
On Thursday night, the Rams’ defense gets another opportunity to prove it should be regarded among the NFL’s best when the San Francisco 49ers and their multidimensional star running back visit SoFi Stadium.
The injury-riddled 49ers (3-1), with victories over the Seattle Seahawks (3-1) and Arizona Cardinals (2-2), are in first place in the NFC West. The Rams (3-1) can move into first place with a victory in the division opener.
A key will be giving McCaffrey the same treatment Barkley received in a crushing defeat by the Philadelphia Eagles, and that Taylor endured during the Rams’ victory over the Indianapolis Colts last Sunday.
Barkley, the reigning NFL offensive player of the year, gained only 46 yards in 18 carries. Taylor, the NFL’s leading rusher, gained 76 yards in 17 carries.
McCaffrey is averaging 56.3 yards rushing and 76.3 yards receiving per game. But the Rams are well-acquainted with his breakaway threat.
“He's a fast dude who can bounce it outside,” Rams edge rusher Jared Verse said. “He can run downhill, he can make you pay if you leave even the smallest crease just like we faced the past two weeks.
“I think the biggest threat that he adds is his ability to receive, like he's leading them in receptions for a reason. He's leading them in yards for a reason. He's a dangerous back when you get to it.”
Since the 49ers outbid the Rams to acquire McCaffrey at the trade deadline in 2022, McCaffrey has played against the Rams twice.
In 2022, he rushed for 94 yards and a touchdown, caught eight passes — including one for a touchdown — and passed for a touchdown in the 49ers’ 31-14 victory.
In 2023, he rushed for 116 yards and a touchdown in a 30-23 victory for the 49ers.
“We know they're going to target him,” Rams defensive coordinator Chris Shula said. “He's going to be the focal point of their offense and it's just a huge challenge.”
McCaffrey, however, will be operating in an offense that will be without key several players because of injuries.
Quarterback Brock Purdy and receivers Ricky Pearsall, Jauan Jennings and Jordan Watkins will not play. Star tight end George Kittle remains on injured reserve for at least one more game.
Mac Jones will start in place of Purdy.
Key injuries
Rams: TE Tyler Higbee (hip, doubtful); OT Rob Havenstein (ankle, doubtful).
49ers: DE Robert Beal (ankle, out). WR Jauan Jennings (ankle/rib, out); WR Ricky Pearsall (knee, out); QB Brock Purdy (toe, out); WR Jordan Watkins (calf, out); DT CJ West (thumb, questionable).
How to watch and listen to Rams vs. 49ers
The Rams and Colts will play at 5:15 p.m. PDT Thursday at SoFi Stadium in Inglewood. The game will be streamed on Amazon Prime nationally and will be shown on Fox in the Los Angeles area. In Southern California, fans can listen to the game on 710 AM and 1330 AM (Español).
Betting lines for Rams vs. 49ers
Who will win Rams vs. 49ers?
Gary Klein’s pick: If Purdy and all of his receivers were available, this would be a close matchup. But without them, the Rams defense should once again assert itself and give quarterback Mathew Stafford and the offense plenty of opportunities.
