Fantasy Football Injury Report Week 6: Amon-Ra St. Brown's wrist; Kyler Murray, Chuba Hubbard updates
Staying up to date on NFL injury news is of the utmost importance for fantasy football success. The article below tracks all fantasy-relevant players currently listed on their team's injury report, and provides fantasy managers with actionable recommendations as new information rolls in.
Check back for updates from Tuesday through Saturday.
Don’t forget: Check out the Rotoworld player news feed for all the latest news, notes, and transactions around the league.
**UPDATED AS OF WEDNESDAY, OCTOBER 8TH AT 7:55 PM ET**
AFC East
◆ Buffalo Bills
The Bills escaped their Week loss to the Patriots without any fantasy-relevant injuries.
◆ Miami Dolphins
Tyreek Hill - WR (knee)
Hill suffered a dislocated knee in the team's Week 4 win over the Jets. His season is over.
Fantasy Impact: Hill's absence likely places additional emphasis on the short-to-intermediate areas of the field, increasing the expected target volume for De'Von Achane, Darren Waller, and Jaylen Waddle. Malik Washington is likely to step into a secondary role and could see his aDOT improve, making him a sneaky potential FLEX option for the remainder of the season. Waddle returned a 6-110-1 line on nine targets in his first game without Hill in Week 5, making him a weekly WR2 option for the remainder of the season.
◆ New England Patriots
Antonio Gibson - RB (knee)
Gibson tore his ACL in the team's Week 5 win over the Bills. His season is over.
Fantasy Impact: Gibson's absence shifts the New England backfield to a two-headed system, paving the way for rookie TreVeyon Henderson to see an increase in opportunities the rest of the season. The presence of established veteran Rhamondre Stevenson caps Henderson's weekly upside, but the former's fumble issues could force the team's hand after Stevenson committed his 10th fumble since the start of the 2024 season in Week 5. Treat Stevenson as a low-upside RB3 while Henderson has paths to RB2 ceiling should his opportunity share see a sudden spike.
◆ New York Jets
Justin Fields - QB (knee)
Fields is practicing in full for Week 6 against the Broncos.
Fantasy Impact: Fields' full practice to begin the week suggests this is not a serious injury. He should be ready to handle his typical dual-threat workload this weekend, but it is worth monitoring his status as the week progresses.
Braelon Allen - RB (knee)
Allen suffered a "pretty serious" knee injury on a kickoff return in the second quarter of the team's Week 4 loss to the Dolphins. He is out indefinitely.
Fantasy Impact: Allen has been a significant contributor in the red zone this season. His absence substantially boosts Breece Hall's upside, who is now a locked-in RB1 in Week 5 against the Cowboys. Backup running back Isaiah Davis can be stashed in 12-team leagues as a high-upside contingency option. Hall gained a season-high 155 yards from scrimmage on 18 opportunities in his first game without Allen in Week 5.
AFC North
◆ Baltimore Ravens
Lamar Jackson - QB (hamstring)
The perennial MVP candidate suffered a hamstring injury in the second half of the team's Week 4 loss to the Chiefs. He is considered week-to-week and could miss multiple games. The Ravens are on bye in Week 7. A Week 8 return is possible. As of Wednesday, he faces an "uphill battle" to play in Week 6.
Fantasy Impact: Jackson led the league with 11 total touchdowns (10 passing and one rushing) at the time of the injury, leaving a significant roster hole to fill in Week 6. Fantasy managers should look to the waiver wire early for a backup plan, with Jaxson Dart serving as a potential fill-in considering his rushing upside. Jackson's expected absence hurts Derrick Henry, Zay Flowers, and Mark Andrews in fantasy.
◆ Cincinnati Bengals
Joe Burrow - QB (toe)
Burrow suffered a Grade III turf toe injury in Week 1. He underwent successful surgery and is likely to miss the next three months.
Fantasy Impact: The Bengals signed veteran Joe Flacco on Tuesday. He should immediately be considered the starter in Cincinnati following Jake Browning's struggles, and he provides a sizable boost to Ja'Marr Chase, Tee Higgins, and Chase Brown's fantasy-scoring upside.
◆ Cleveland Browns
Cedric Tillman - WR (hamstring)
The Browns' No. 2 wide receiver strained his hamstring in Week 4. He was placed on injured reserve shortly thereafter and will miss at least four games.
Fantasy Impact: Rookie quarterback Dillon Gabriel relied upon tight ends, David Njoku (nine targets) and Harold Fannin (four targets), and wide receiver Isaiah Bond (six targets) in his first career start last week. We do not yet know who will start under center in Week 6, but those three pass catchers are seemingly separating from veteran wide receiver Jerry Jeudy (three targets).
◆ Pittsburgh Steelers
Jaylen Warren - RB (knee)
Warren is reportedly expected to return in Week 6 after missing the team's Week 4 win over the Vikings in Dublin. He promisingly practiced in full on Wednesday.
Fantasy Impact: Warren looks primed to return following one missed contest and the team's Week 5 bye. He got up to an 80% snap rate in Week 3 and could immediately return to a featured role for the Steelers. He carries Weekly RB2 upside. Steelers No. 2 running back Kenneth Gainwell should be stashed on benches after totaling 134 scrimmage yards and two touchdowns in Week 4.
Calvin Austin - WR (shoulder)
Calvin Austin injured his shoulder in the team's Week 4 win over the Vikings. He was hospitalized with the injury and is expected to miss multiple games, per Steelers insider Gerry Dulac.
Fantasy Impact: Austin received good news on the injury when X-rays came back negative, but his absence is expected to extend through the team's Week 5 bye. Ben Skowronek, Scotty Miller, and Roman Wilson will all likely be tasked with filling the void for as long as the team's WR2 remains sidelined.
AFC South
◆ Houston Texans
Joe Mixon - RB (foot)
Mixon was placed on the Non-Football Injury list ahead of Week 1 and is eligible to be activated in Week 5. The team stated that the veteran back is "making progress" and will be re-evaluated in a few weeks.
Fantasy Impact: Veteran Nick Chubb reminded us all that he is not going away, leading the backfield with 11 carries against the Ravens in Week 5. Rookie Woody Marks remains the upside play in Mixon's absence, but he handled just seven carries in Week 5 and the Texans predominantly view Marks as a "passing-game back." This remains a messy situation for fantasy behind one of the league's worst run-blocking offensive lines.
Cade Stover - TE (foot)
The Texans placed Stove on injured reserve before Week 2.
Fantasy Impact: Stover will miss at least four games. His absence should add one or two targets to tight end Dalton Schultz's weekly workload. The uptick is not enough to make Schultz a reliable TE1.
◆ Indianapolis Colts
Alec Pierce - WR (concussion)
Pierce practiced in full on Wednesday, theoretically putting him on track to play in Week 6 against the Cardinals. He notably practiced in full twice last week before being downgraded to a non-participant and ruled out on Friday.
Fantasy Impact: It was Ashton Dulin who filled Pierce's vacated role in Week 5 following mental mistakes from Adonai Mitchell a week prior. Expect Pierce to immediately reclaim a starting perimeter role opposite Michael Pittman once healthy.
◆ Jacksonville Jaguars
Brenton Strange - TE (hip)
Strange was unable to finish the team's Week 5 game against the Chiefs due to a hip injury. The team placed him on injured reserve the very next day. He will be eligible to return in Week 11.
Fantasy Impact: Strange currently stands as fantasy's TE20 in PPR scoring, but his 15.3% team target share ties for second among Jaguars pass catchers. Journeyman Hunter Long stepped into the primary pass-catching role following Strange's departure, but he is unlikely to become a viable starter. Fantasy managers should expect the Jaguars' established wide receivers and running backs to compete for chunks of Strange's vacated target share.
◆ Tennessee Titans
Tyjae Spears - RB (ankle)
Spears made his season debut in Week 5 after being activated from injured reserve Saturday. He played just 25% of the team's offensive snaps, but the team is expected to increase his participation moving forward.
Fantasy Impact: Backfield mate Tony Pollard saw 19, 21, 20, and 17 running back opportunities in the first four games of the season, and dropped to 17 in Spears' first game action. We expect Pollard's days of workhorse usage to be behind him after head coach Brian Callahan said Spears' usage will grow moving forward.
AFC West
◆ Denver Broncos
The Broncos did not experience any major injuries in their Week 5 win over the Eagles.
◆ Kansas City Chiefs
Xavier Worthy - WR (ankle, shoulder)
Worthy played in Week 5 after coming into the game listed as questionable for an ankle injury. He appeared to aggravate the injury in the third quarter but finished the game. He is practicing in full for Week 6 against the Lions.
Fantasy Impact: Worthy continues to gut out multiple injuries and managed to play 77% of the team's offensive snaps in their loss to the Jaguars. Fantasy managers will want to track his practice participation throughout the week ahead of a must-win game against the Lions in Week 6. He remains a WR2 if active, at least for as long as Rashee Rice remains out.
Kareem Hunt - RB (calf)
Hunt is practicing in full for Week 6 against the Lions, so this is unlikely to be an issue.
Fantasy Impact: Hunt should continue dominating carries inside the opponent's five-yard line this week, assuming he is active. His practice participation is worth following, but he should be good to go.
◆ Las Vegas Raiders
Michael Mayer - TE (concussion)
Mayer suffered a concussion in the team's Week 3 loss to the Commanders and did not play in Week 4 or Week 5. He is expected to return in Week 6.
Fantasy Impact:Ian Thomas was forced into a featured role for the reeling Raiders in Week 5, but is likely to return to fantasy oblivion moving forward. Mayer's fantasy value is tied to the health of Brock Bowers, who also missed Week 5 with a PCL sprain and bone bruise (more below).
Brock Bowers - TE (knee)
Bowers went limited-DNP-DNP in practice last week and was ultimately held out for the Raiders' Week 5 loss to the Colts. He did not practice on Wednesday.
Fantasy Impact: Bowers has been slowed by a nagging knee injury, involving a PCL sprain and a bone bruise, that he attempted to play through until Week 5. The team elected to hold him out last week after it was revealed that the only remedy is rest. Fantasy managers will want to track his practice participation closely ahead of a Week 6 matchup with the Titans. Michael Mayer should step into a featured role in the offense if Bowers can't go again.
◆ Los Angeles Chargers
Najee Harris - RB (Achilles)
Harris ruptured the Achilles tendon in his left leg during the Chargers' Week 3 win over the Broncos. His season is done.
Omarion Hampton - RB (ankle)
Hampton was placed on injured reserve this week after suffering an ankle injury in the team's Week 5 loss to the Commanders. He will miss the next four games, at minimum.
Fantasy Impact: Los Angeles' backfield injuries leave Hassan Haskins and Kimani Vidal atop the depth chart. Both players saw three carries and one target following Hampton's departure in Week 5, although there is a connection between Haskins and head coach Jim Harbaugh, considering Haskins played for him at Michigan. Fantasy managers could do worse than taking a flier on either player.
Will Dissly - TE (knee)
Dissly missed Week 3 due to a knee injury, allowing rookie tight end Oronde Gadsden II to enter the lineup. Dissly did not play in Week 4 or Week 5.
Fantasy Impact: Gadsden caught five passes for 46 yards in Week 3. He caught just 2-of-3 targets for 16 yards in Week 4 and caught his only target for 11 yards in Week 5, making this a low-upside situation for as long as all three primary wide receivers remain healthy.
Quentin Johnston - WR (hamstring)
This is a new injury for Johnston, who was limited at Wednesday's practice.
Fantasy Impact: This one is worth following closely. It is unknown when he suffered the injury. If it occurred on Wednesday, his Week 6 availability would be jeopardized. Slot receiver Ladd McConkey would stand to benefit if Johnston were to miss time.
NFC East
◆ Dallas Cowboys
CeeDee Lamb - WR (ankle)
Lamb suffered a high-ankle sprain in the team's Week 3 blowout loss to the Bears. He did not play in Week 4 or Week 5 and remains sidelined as of Wednesday.
Fantasy Impact: The Cowboys will be without the primary cog of the offense for an estimated 3-4 weeks, and are also missing two offensive linemen, which could limit their ability to run the football effectively. Injuries to their defense keep their likeliest game environments as shootouts, which should benefit George Pickens and tight end Jake Ferguson in the immediate future. Treat Pickens as a borderline WR1/2 and Ferguson as a TE1 in the coming weeks. Cowboys wide receiver Ryan Flournoy earned eight targets with Lamb and KaVontae Turpin (ankle) sidelined. Flournoy could warrant desperation-FLEX consideration in Week 6.
Miles Sanders - RB (ankle/knee)
Sanders was injured in Week 4 and did not play in Week 5. He was limited on Wednesday, which bodes positively for his Week 6 availability.
Fantasy Impact: Rookie Jaydon Blue was active for the first time this season in Week 5 but played just 11 offensive snaps. Veteran Javonte Williams continues to operate in a near workhorse role. Blue should still be stashed on benches after faring well in pass-protection last week. If Sanders can resume practicing in full by Friday, the Cowboys' game-day inactive list should help clarify the current backfield depth chart.
◆ New York Giants
Malik Nabers - WR (knee)
Nabers suffered a torn ACL in the team's Week 4 win over the Chargers and will miss the remainder of the 2025 season.
Fantasy Impact: The injury could not have come at a worse time for the Giants after they moved to rookie quarterback Jaxson Dart under center. Nabers' absence will make it difficult to consistently move the football, lowering the upside of all remaining healthy players. Nabers makes for a solid trade target for dynasty managers looking to rebuild this season.
Tyrone Tracy - RB (shoulder)
Tracy will play in Week 6's Thursday Night Football game against the Eagles.
Fantasy Impact: Tracy missed the previous two games after suffering a shoulder injury in Week 3. It sounds like he is primed for a return when the Giants take the field on Thursday against the Eagles, but would be nothing more than a desperation-FLEX option in his first game back.
Jaxson Dart - QB (hamstring)
Dart strained his hamstring in Week 4 but played in Week 5. Head coach Brian Daboll said he expects the rookie signal caller to play on Thursday against the Eagles.
Fantasy Impact: Dart should be good to go in Week 6, as long as he remains setback-free. He remains a locked-in QB2 with rushing-induced QB1 upside while active.
Darius Slayton - WR (hamstring)
Slayton has been ruled out for Week 6 against the Eagles after injuring his hamstring in Week 5.
Fantasy Impact:Jalin Hyatt and Beaux Collins should be tasked with perimeter roles for a Giants team now without their top two receiving options. Tight end Theo Johnson caught 6-of-7 targets for 33 yards and two touchdowns a week ago and carries more upside than any wide receiver on the roster. Fellow tight end Daniel Bellinger warrants DFS consideration after leading the team in receiving (52 yards) last week.
◆ Philadelphia Eagles
Saquon Barkley - RB (knee)
Barkley will play in Week 6 against the Giants after dealing with "general soreness" in his knee this week.
Fantasy Impact: Fantasy managers are starting Barkley if he is active, regardless of matchup or other options. He promisingly practiced in full on Wednesday.
◆ Washington Commanders
Terry McLaurin - WR (quad)
Head coach Dan Quinn is "optimistic" about McLaurin playing in Week 6 after the veteran wide receiver missed the previous two games.
Fantasy Impact: The team sorely needs their vertical threat back on the field after struggling to stress teams downfield the previous three games. McLaurin would reclaim WR2 honors in fantasy circles if active.
Noah Brown - WR (groin, knee)
Brown missed the team's previous three games with groin and knee injuries.
Fantasy Impact:Jaylin Lane and Luke McCaffrey are splitting the vacated role but are not fantasy relevant.
NFC North
◆ Chicago Bears
Colston Loveland - TE (hip)
Loveland suffered a hip injury that is not considered serious in the team's Week 3 win over the Cowboys. He did not play in Week 4 after failing to make it through a pre-game workout. The team's Week 5 bye should allow him to return to action against the Commanders in Week 6.
Fantasy Impact: Loveland has yet to live up to the offseason hype while playing behind Cole Kmet and can safely be returned to the waiver wire.
◆ Detroit Lions
Amon-Ra St. Brown - WR (wrist)
St. Brown appeared on Wednesday's injury report as a non-participant.
Fantasy Impact: St. Brown still has time to get his body ready for the Lions' Week 6 game against the Chiefs, but this is concerning. Lions No. 3 wide receiver Kalif Raymond (neck) was also sidelined to begin the week. Field-stretching wide receiver Jameson Williams' rostership rate has decreased by 4.0 percent on Yahoo this week. It is worth checking to see if he is available in your league. Should both St. Brown and Raymond miss Week 6, Williams and exciting rookie wide receiver Isaac TeSlaa would operate as the de facto Nos. 1 and 2 wide receivers. TeSlaa could be started in the FLEX in that scenario.
◆ Green Bay Packers
Jayden Reed - WR (collarbone/foot)
Reed fractured his collarbone in the Packers' Week 2 game against the Commanders and was already playing through a Jones fracture in his foot. When news of the expected collarbone surgery broke, the Packers were reportedly hoping to get Reed back in November. Reed then revealed that he underwent surgery to correct his Jones fracture as well. It is unknown whether this will extend his recovery timeline.
Fantasy Impact: Reed can be stashed in injured reserve spots, but he does not need to be held in leagues without them. Wide receivers Romeo Doubs and Matthew Golden are on the FLEX radar.
Christian Watson - WR (knee)
Watson was designated for return from injured reserve and returned to the practice field on Monday. He was officially limited on Wednesday.
Fantasy Impact: We expect Watson to take most of the 21-day window to ramp up before seeing game action, and will then likely experience a dip in production after a torn ACL. He may not be a viable fantasy commodity until 2026.
Jordan Love - QB (ankle)
Love is practicing in full for Week 6 against the Bengals.
Fantasy Impact: Love should be good to go this week. He is a borderline QB1/2 against the Bengals' fantasy-friendly defense.
◆ Minnesota Vikings
J.J. McCarthy - QB (ankle)
McCarthy sustained a high-ankle sprain in the team's Week 2 loss to the Falcons. He is expected to return to practice following the team's Week 6 bye.
Fantasy Impact: The Vikings appear primed to get their starting quarterback back on the field out of their Week 6 bye. Fill-in starting quarterback Carson Wentz will undergo further evaluation after injuring his shoulder in Week 5. McCarthy carries QB1 upside if healthy.
Aaron Jones - RB (hamstring)
The Vikings placed Jones on injured reserve. He will be eligible to return after missing four games in Week 8. The Vikings are on bye in Week 6.
Fantasy Impact: Running back Jordan Mason is operating as the clear-cut lead back, while running back Zavier Scott operates as the passing game specialist. Scott warrants deep-league, PPR consideration.
Don’t forget: Check out the Rotoworld player news feed for all the latest news, notes, and transactions around the league.
NFC South
◆ Atlanta Falcons
Darnell Mooney - WR (hamstring)
Mooney left the team's Week 4 win over the Commanders with a hamstring injury. The team's Week 5 bye should afford him the opportunity to heal enough to play against the Bills in Week 6.
Fantasy Impact: NFL Network's Ian Rapoport reports Mooney is unlikely to miss any time after a low-grade hamstring injury. Fantasy managers can continue to deploy Mooney as a FLEX option moving forward.
◆ Carolina Panthers
Ja’Tavion Sanders - TE (ankle)
Sanders suffered a high-ankle sprain in the team's Week 3 win over the Falcons and did not play in Week 4 or Week 5. He was limited on Wednesday.
Fantasy Impact: If active, Sanders can be treated as a high-end TE2.
Chuba Hubbard - RB (calf)
Hubbard suited up in Week 4 but missed the team's Week 5 win over the Dolphins. Head coach Dave Canales labeled him "day-to-day" entering Week 6 preparations. He was sidelined on Wednesday.
Fantasy Impact: Veteran backup Rico Dowdle handled the bulk of the backfield work for the Panthers in Week 5 and rumbled his way to 206 yards and a score on the ground against the Dolphins. This is an interesting situation to follow. Dowdle appears to be on track for another featured role in Week 6. If he continues playing well, Panthers coaches could consider rewarding him with the starting role even after Hubbard returns.
Jalen Coker - WR (quad)
Coker was activated from injured reserve and promisingly practiced in full on Wednesday, putting him on track to play, barring a setback.
Fantasy Impact: The Panthers' slot receiver should be added wherever available. It may take him a week to get up to speed, but he should quickly assume No. 2 pass-catcher duties.
◆ New Orleans Saints
Alvin Kamara - RB (ankle)
Kamara reportedly sprained his ankle in Week 5 and felt good enough to join his teammates at the beginning of Wednesday's practice. He ended up leaving early, however, after experiencing soreness.
Fantasy Impact: Kamara is considered "day-to-day" and should be active for Week 6. It is worth checking on No. 2 running back Kendre Miller's availability, though. He totaled 11 touches to Kamara's 12 last week.
◆ Tampa Bay Buccaneers
Chris Godwin Jr. - WR (fibula)
Godwin did not practice on Wednesday.
Fantasy Impact: This one is a bit strange. Godwin notably fractured his fibula when he dislocated his ankle last year, but the team had been listing him with an ankle injury this season, not a "fibula." He practiced in full last week, so today's DNP downgrade is concerning. Hopefully, this is just a rest day for Godwin and not an actual re-injury.
Bucky Irving - RB (foot/shoulder)
Irving is considered week-to-week after injuring his foot in Week 4. He was out for Week 5 and remained sidelined this week at Wednesday's practice.
Fantasy Impact:Rachaad White vaults into RB2 territory while Sean Tucker could push for FLEX status in a rotational rushing role. Both players should be rostered.
Jalen McMillan - WR (neck)
McMillan remains on injured reserve with a neck injury suffered in the preseason.
Fantasy Impact: McMillan's absence paved the way for rookie wide receiver Emeka Egbuka to see featured usage in the offense right out of the gate. The talented rookie remains in the weekly WR2 discussion after scoring three touchdowns in his first two professional games.
Mike Evans - WR (hamstring)
Evans is expected to miss 3-4 weeks after injuring his hamstring in Week 3.
Fantasy Impact: Rookie wide receiver Emeka Egbuka suddenly finds himself a WR2 with WR1 upside in his fourth professional contest.
NFC West
◆ Arizona Cardinals
Kyler Murray - QB (foot)
Murray injured his foot on a fourth-quarter fumble. Head coach Jonathan Gannon said the team would "monitor his foot throughout the week." Unfortunately, he began the week sidelined.
Fantasy Impact: Murray still doesn't have a weekly finish greater than QB16 through five games, making him an expendable asset in one-QB leagues.
Trey Benson - RB (knee)
Benson has already undergone surgery after injuring his meniscus in Week 4. He is expected to miss 4-to-6 weeks.
Fantasy Impact: Backup running back Michael Carter referred to himself as the new starter when speaking to media members. Fellow backup running back Emari Demercado will likely rotate in on passing downs. Carter proved to be an RB2 in Week 5 when he saw 58% of the team's offensive snaps and handled 18 of 25 running back carries against the Titans.
James Conner - RB (ankle)
Conner suffered a season-ending foot injury in Week 3.
Fantasy Impact: See: Trey Benson.
◆ Los Angeles Rams
The Rams remain healthy heading into a Week 6 game against the reeling Ravens.
◆ San Francisco 49ers
George Kittle - TE (hamstring)
The 49ers placed Kittle on injured reserve Tuesday, meaning he will miss at least the next four games. Head coach Kyle Shanahan said Kittle is a "long shot" to have his practice window opened ahead of Week 6.
Fantasy impact: 49ers backup tight end Jake Tonges is quietly third on the team with a 13.7 percent target share and is coming off consecutive TE1 finishes. He is a reasonable TE1 streamer until Kittle returns.
Brock Purdy - QB (shoulder, toe)
Purdy is considered week-to-week after suffering a setback in Week 4.
Fantasy Impact: 49ers backup quarterback Mac Jones remains a borderline QB1/2 while Purdy is sidelined. Although Jones is rehabbing a PCL sprain in his knee, he is playing effectively.
Jauan Jennings - WR (ankle/shoulder)
Jennings did not play against the Rams in Week 5. He was sidelined on Wednesday.
Fantasy Impact: Fantasy managers will want to monitor the situation closely as preparations for Week 6 progress. NFL Network's Ian Rapoport reported last week that Jennings "could be back" for Week 6 against the Buccaneers. Wide receiver Kendrick Bourne earned 11 targets in Week 5 and would again operate as the team's No. 1 wide receiver if Jennings and Pearsall, discussed below, cannot play.
Ricky Pearsall - WR (knee)
Pearsall did not play in week 5 against the Rams. He did not practice on Wednesday.
Fantasy Impact: Fantasy managers will want to monitor the situation closely as preparations for Week 6 progress. NFL Network's Ian Rapoport also reported last week that Pearsall "could be back" for Week 6 against the Buccaneers.
◆ Seattle Seahawks
The Seahawks avoided any major injuries in their Week 5 loss to the Buccaneers.