The Texans have their first lead of Thursday Night Football.
Christian Kirk caught his first touchdown of the season, catching a 2-yard pass from Davis Mills with 3:47 left in the first half.
The Texans drove 77 yards in 12 plays following Bills kicker Matt Prater's 44-yard field goal. The Bills had a facemask and an illegal contact penalty on the drive.
Mills also threw a 24-yard pass to Nico Collins for the biggest play in the drive.
Mills is 4-of-13 for 40 yards and a touchdown.
Woody Marks has seven carries for 46 yards.
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