Week 6 of the NFL season has arrived, and it's time to get those bets in. 

We've compiled where the public is betting at BetMGM sportsbooks, along with some notable wagers, and asked around at several other books to find out where the sharp action has come in for this weekend's games.

[For all of our NFL betting content, be sure to check out our new betting hub right here.]

Week 6 NFL best bets| Trends | Survivor picks

Week 6 odds

Sunday

Sunday

9:30 a.m. ET

Denver Broncos (-7.5, 43.5) at New York Jets in London

1 p.m. ET

Cleveland Browns at Pittsburgh Steelers (-6, 38.5)

Arizona Cardinals at Indianapolis Colts (-7, 47)

Los Angeles Chargers (-4.5, 43.5) at Miami Dolphins

New England Patriots (-3.5, 46) at New Orleans Saints

Dallas Cowboys (-3, 49.5) at Carolina Panthers

Seattle Seahawks at Jacksonville Jaguars (-1, 47.5)

Los Angeles Rams (-7.5, 44.5) at Baltimore Ravens

4 p.m. ET

Tennessee Titans at Las Vegas Raiders (-4, 41.5)

Cincinnati Bengals at Green Bay Packers (-14.5, 44.5)

San Francisco 49ers at Tampa Bay Buccaneers (-3, 47.5)

Sunday Night Football

Detroit Lions at Kansas City Chiefs (-2.5, 53)

Monday

Buffalo Bills (-4.5, 50) at Atlanta Falcons

Chicago Bears at Washington Commanders (-4, 50)

Bye-week teams: Vikings, Texans

Public betting splits

Here is where the betting public has landed on Week 6 games at BetMGM sportsbooks.

Five most-bet games (by total number of wagers)

1. Lions +2.5

2. Colts -7.5

3. Steelers -5.5

4. Bills -4.5

5. Broncos -7.5

Five most-bet games (by total dollars wagered)

1. Colts -7.5

2. Lions +2.5

3. Steelers -5.5

4. Patriots -3.5

5. Cowboys -3

Most-bet totals (by total number of wagers)

1. Detroit Lions at Kansas City Chiefs Over 53

2. Buffalo Bills at Atlanta Falcons Over 50

3. Denver Broncos at New York Jets Under 43.5

4. Cleveland Browns at Pittsburgh Steelers Over 38.5

5. Los Angeles Rams at Baltimore Ravens Over 44.5

Most-bet underdogs to win (by total number of wagers)

1. Detroit Lions +115

2. Cincinnati Bengals +700

3. Baltimore Ravens +325

4. New York Jets +300

5. San Francisco 49ers +140

From the bookmakers

"The Lions are the most bet team to cover as underdogs on 'Sunday Night Football.' Outside of Detroit, nearly every favorite is receiving a majority of bets to cover. This week features 11 spreads greater than a field goal and, generally, the book is looking for underdogs to cover." — Christian Cipollini, BetMGM trading manager

Seahawks-Jags

Thomas Gable, Borgata sportsbook director: "Quick turnaround for Jaguars off Monday night. We opened them -1.5, early Seattle money here so down to -1. Total bet up from 44.5 to 46.5. I wouldn’t be surprised to see the favorite flip. I could see this closing a pick-em."

49ers-Bucs

Gable: “We opened Tampa Bay -2.5, they’ve been bet up to 3. Total up from 46.5 to 47.5. Early money on Tampa Bay, not much on San Francisco, but not a ton has been written on this game overall. I think this will stay right around 3.”

Joey Feazel, Caesars Sportsbook NFL trading lead: “Brock Purdy again questionable dealing with that toe injury. Poor Mac Jones was beat up on Thursday. 49ers pulled off a very big victory against the Rams — a lot of injuries and still dealing with them going into this game. Bucs have been dealing with injuries as well. We’re seeing pretty much two-way action, a little more towards the 49ers. Line has moved towards the Bucs. This opened -1.5 on Sunday, now up to -3. Line movement towards Purdy not playing. Total wise, not much movement and not action." 

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Rams-Ravens

Gable: “We opened Rams -7.5, that’s where it still sits. Total down half a point. Public is all over the Rams here. We know no Lamar Jackson in this one, and it's been pretty much one-way traffic on the Rams. They’ve been a popular teaser play as well. It could get to 8, 8.5. If this continues to get bet one-way, we’ll probably test it out."

Feazel: “So far not a lot people wanting to touch the game, especially on the side. What people have been eyeing has been towards the over. Nobody’s bingo card was Baltimore being towards the bottom of the league on D so far, but injuries have been a problem. Mostly seeing over money, not a lot of people running to the window to lay 7.5 with the Rams or back Ravens. A few weeks ago, Ravens were atop most people’s power ratings. Definitely ML parlays tied to Baltimore."

Lions-Chiefs

Gable: “The Lions have been looking great since that Week 1 loss to Green Bay — they’ve been steamrolling everyone. We opened Chiefs -1.5, line moved to -2.5. Lions are facing major injuries in their secondary. Mostly recreational money on this game, and it has been on Detroit. Total up from 49.5 to 52.5. If the Lions were at full strength coming into the game, I’d have this as a pick, maybe Chiefs a half-point favorite.”

Feazel: “We have seen some movement on the total, opening at 49.5 now up to 52.5. That’s pretty much how it’s been for every Lions game so far. Seeing mostly over action to this point, we did see some Lions money come in early, but we’ve taken a flurry of Chiefs bets. This is the last game that the Chiefs will be missing Rashee Rice. I expect to see two-way action here with the Lions being a public darling. Even with the Chiefs in this spot, I still anticipate heavy Lions action, especially on the money line. I don’t see this going up to 3. This is going to be a very highly-bet game. Some sharp action on the Chiefs, respecting Kansas City’s defense and 'Sunday Night Football' in Kansas City is about one of the best home-field advantages you’ll get.”

Sharp action

It's always notable where respected bettors have landed on this week's games. While these prices may not currently be available at all sportsbooks, knowing where sharps have wagered can also be instructive for in-game wagering.

Yahoo Sports conversed with several bookmakers over the course of the week, and here is where some sharp action has been (and the numbers it came in at):

• Dolphins +5.5, Chargers-Dolphins Under 44.5

• Titans-Raiders Under 42.5 

• Bucs -2.5

• Ravens +7.5

• Broncos -7, NY Jets +7.5

• Panthers +3.5

• Chiefs -1.5, Lions-Chiefs Over 51, 51.5

• Bills -3.5, -4

Big bets

We'll be keeping track of six-figure (and larger) Week 6 NFL bets from sportsbooks, as well as if they end up cashing.

• $339,000 on New York Giants +7.5 at Caesars (won)